The route connecting Knoxville, Tennessee, and Cincinnati, Ohio, represents a major transportation hall within the Southeastern and Midwestern United States. It facilitates the motion of individuals and items between these two main cities, spanning a distance of roughly 300 miles.
This hyperlink is significant for financial exercise, enabling commerce, tourism, and private journey. Traditionally, the connection has advanced from early roadways to trendy interstate highways, reflecting developments in infrastructure and transportation expertise. The supply of environment friendly routes contributes to regional progress and accessibility.